Sikeston in Scott County, Missouri — The American Midwest (Upper Plains)
The Sikeston Depot
116 West Malone
The National Registry of
Historic Places
Topics. This historical marker is listed in these topic lists: Notable Buildings • Railroads & Streetcars.
Location. 36° 52.575′ N, 89° 35.393′ W. Marker is in Sikeston, Missouri, in Scott County. It is on West Malone Avenue (Business U.S. 60) just west of North New Madrid Street, on the right when traveling west. Marker is located on the south side of the Sikeston Depot Museum, just right/east of the main entrance. Touch for map. Marker is at or near this postal address: 116 West Malone Avenue, Sikeston MO 63801, United States of America. Touch for directions.
Regionally, this marker is in the Missouri Bootheel. It is also in the American Mississippi Delta, in the Ozarks, in the Lewis & Clark Corridor, in the Corn Belt, and in the Great River Road Region. Globally, it is in North America, the Western Hemisphere, the Western World, and the Anglosphere. Historically, it finds itself in what was once the territory of the Mississippian Culture, the Louisiana Purchase, and the Antebellum South.
Other nearby markers. At least 3 other markers are within walking distance of this marker: Legion Square (about 300 feet away, measured in a direct line); a different marker also named Legion Square (about 500 feet away); El Camino Real (approx. 0.3 miles away).
Regarding The Sikeston Depot. National Register of Historic Places #00001549, as Sikeston St. Louis, Iron Mountain and Southern Railway Depot. Currently home to the Sikeston Depot Museum & Cultural Center.
Also see . . .
1. Sikeston Station. Wikipedia entry (Submitted on May 21, 2025, by Larry Gertner of New York, New York.)
2. Sikeston Depot Museum & Cultural Center. Website homepage (Submitted on May 21, 2025, by Larry Gertner of New York, New York.)
3. Sikeston St. Louis, Iron Mountain and Southern Railway Depot.
Also known as the Sikeston Missouri Pacific Railroad Depot. It was built in 1916-1917 by the St. Louis, Iron Mountain and Southern Railway, and is a one-story, rectangular brick building measuring 24 feet by 100 feet. It has a hipped, red ceramic tile roof with wide eaves supported by curvilinear brackets.(Submitted on January 24, 2022, by Cosmos Mariner of Cape Canaveral, Florida.)
Credits. This page was last revised on May 21, 2025. It was originally submitted on January 24, 2022, by Cosmos Mariner of Cape Canaveral, Florida. This page has been viewed 595 times since then and 49 times this year. Photos: 1, 2, 3, 4, 5, 6. submitted on January 24, 2022, by Cosmos Mariner of Cape Canaveral, Florida.





