St. Charles in St. Charles County, Missouri — The American Midwest (Upper Plains)
The Mother-in-Law House
Topics. This historical marker is listed in this topic list: Architecture. A significant historical year for this entry is 1866.
Location. 38° 46.654′ N, 90° 28.988′ W. Marker is in St. Charles, Missouri, in St. Charles County. It is on South Main Street north of Pike Street, on the right when traveling north. Touch for map. Marker is at or near this postal address: 500 South Main Street, Saint Charles MO 63301, United States of America. Touch for directions.
Regionally, this marker is in the Missouri River Corridor and in Greater St. Louis. It is also in the American Midwest, in the Lewis & Clark Corridor, in the Corn Belt, and in the Great River Road Region. Globally, it is in North America, the Western Hemisphere, the Western World, and the Anglosphere. Historically, it finds itself in what was once the territory of the Mississippian Culture, the Louisiana Purchase, and the Antebellum South.
Other nearby markers. At least 8 other markers are within walking distance of this marker: History of 426 South Main Street (within shouting distance of this marker); Glenday / Zeisler Home
this page online
Photographed by Craig Doda, September 12, 2026
3. The Mother-in-Law House Marker
Credits. This page was last revised on September 23, 2026. It was originally submitted on October 13, 2018, by Devry Becker Jones of Washington, District of Columbia. This page has been viewed 657 times since then and 52 times this year. Last updated on September 22, 2026, by Craig Doda of Napoleon, Ohio. Photos: 1, 2. submitted on October 13, 2018, by Devry Becker Jones of Washington, District of Columbia. 3. submitted on September 22, 2026, by Craig Doda of Napoleon, Ohio.
