Grant's Drug Store
Plaque 1
This structure is also known as the "Pilaster House" named for the flat columns on the exterior. It is historically significant for three reasons:
It was prefabricated in Cincinnati, Ohio, its pieces shipped by steamboat. It arrived in 1836 and was erected by James Brady, later the first mayor of Hannibal.
Dr. Orville Grant, his wife and his mother-in-law lived upstairs. In 1846, because of financial problems, the Clemens family was forced to leave their home and moved across the street with the Grants. In March of 1847, Mr. Clemens rode by horse to the county seat of Palmyra, Missouri, and was caught in a sleet storm. He contracted pneumonia and died in one of the upstairs rooms.
Upon his father's death, young Sam Clemens' mother could no longer afford the 25 cents per week she paid for his education. Sam was forced to leave school and earn room and board as a printer;s apprentice at the age of eleven. This building stands as a testament to the resilience of this young boy who would grow up to become America's most beloved author, Mark Twain.
The Pilaster House was given to the City of Hannibal in 1956 by Mrs. Sarah Mahan. It was restored and opened to the public in 1959. In 2009 the building was placed on Missouri Preservation's "Most Endangered Buildings" list.
The Mark Twain Boyhood Home
& Museum has the responsibility of caring for Grant's, which is on the National Register of Historic Places. We are relying upon donations from concerned citizens to restore this important historical landmark and keep it open for future generations. Will you please donate?Plaque 2
Grant's Drug Store (aka; Pilaster House) was named to Missouri Preservation's "Most Endangered Buildings" list in 2009. Emergency repairs by volunteers saved the building temporarily, but it is now in dire need of a complete restoration and cannot be reopened to the public until such a restoration is complete. This building is vital to preserving the legacy of Mark Twain.
We invite visitors to view the old time drug store display through the windows. Donations toward the restoration project are gratefully accepted. The Mark Twain Boyhood Home & Museum receives no tax dollars to support its historic preservation efforts and must rely on the generosity of Mark Twain fans from around the world.
Thank you for supporting our preservation efforts.
Topics. This historical marker is listed in this topic list: Notable Buildings. A significant historical month for this entry is March 1847.
Location. 39° 42.716′ N, 91° 21.445′ W. Marker is in Hannibal, Missouri, in Marion County. It is at the intersection of Main Street and Hill Street, on the left when traveling north
Regionally, this marker is in Missouri’s Mark Twain Country. It is also in the American Midwest, in the Lewis & Clark Corridor, in the Corn Belt, and in the Great River Road Region. Globally, it is in North America, the Western Hemisphere, the Western World, and the Anglosphere. Historically, it finds itself in what was once the territory of the Mississippian Culture, the Louisiana Purchase, and the Antebellum South.
Other nearby markers. At least 8 other markers are within walking distance of this marker: McDaniel's Candy Store (a few steps from this marker); a different marker also named Grant's Drug Store (a few steps from this marker); Henry Collins Building (a few steps from this marker); Joshua Mitchell Building (a few steps from this marker); New Cash Store (a few steps from this marker); Mark Twain's Father's Law Office (within shouting distance of this marker); Abner Nash Building (within shouting distance of this marker); Mark Twain (within shouting distance of this marker). Touch for a list and map of all markers in Hannibal.
More about this marker. As of 2020, the markers have been removed from windows.
Regarding Grant's Drug Store. Building contributes to the Mark Twain National Register Historic District.
Also see . . . Mark Twain Historic District National Register Nomination Form. (Submitted on September 20, 2020, by William Fischer, Jr. of Reynoldsburg, Ohio.)
Credits. This page was last revised on September 20, 2020. It was originally submitted on August 27, 2012, by Bill Pfingsten of Bel Air, Maryland. This page has been viewed 1,253 times since then and 36 times this year. Photos: 1, 2, 3. submitted on August 27, 2012, by Bill Pfingsten of Bel Air, Maryland. 4. submitted on September 20, 2012, by M. Bowyer of Indianapolis, Indiana.



