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Oxford in Lafayette County, Mississippi — The American South (East South Central)
 

Dr. Thomas Isom's Drug Store and Medical Office

 
 
Dr. Thomas Isom's Drug Store and Medical Office Marker image. Click for full size.
Photographed by Duane and Tracy Marsteller, April 1, 2023
1. Dr. Thomas Isom's Drug Store and Medical Office Marker
Inscription.
Site of the
drug store and medical office
of Dr. Thomas Dudley Isom


Considered to be the first white settler
of this region
Building circa 1889 – restored 1988

The Oxford Courthouse Square Historic District
National Register of Historical Places
United States Department of the Interior

 
Topics. This historical marker is listed in these topic lists: ArchitectureIndustry & CommerceScience & Medicine. A significant historical year for this entry is 1889.
 
Location. 34° 22.016′ N, 89° 31.15′ W. Marker is in Oxford, Mississippi, in Lafayette County. It is on Courthouse Square west of North Lamar Boulevard, on the right when traveling west. Touch for map. Marker is at or near this postal address: 110 Courthouse Square, Oxford MS 38655, United States of America. Touch for directions.

Regionally, this marker is in the North Mississippi Hills. It is also in the American South and specifically in the Deep South. Globally, it is in North America, a Gulf of Mexico state, the Western Hemisphere, the Western World, and the Anglosphere. Historically, it finds itself in what was once the territory of the Mississippian Culture, one of the Confederate States of America, and the Antebellum South.

Other nearby markers. At least 8 other markers are within walking distance of this marker: Oxford & Lafayette County Blues (a few steps from this marker); Lafayette County Courthouse (within shouting distance of this marker); Lynching in America / Lynching in Lafayette County (about 300 feet away, measured in a direct line); Lafayette County Confederate Monument (about 300 feet away); Oxford (about 300 feet away); St. Peter's (1851), Episcopal
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(about 600 feet away); Oxford Cemetery (about 700 feet away); First Baptist Church (approx. 0.2 miles away). Touch for a list and map of all markers in Oxford.
 
Also see . . .
1. Oxford Courthouse Square Historic District. National Register nomination (PDF) and photographs (separate PDF) submitted for the district, which was listed in 1980. (National Park Service) (Submitted on April 6, 2023, by Duane and Tracy Marsteller of Murfreesboro, Tennessee.) 

2. Dr. Thomas Dudley Isom. Find a Grave entry on the physician contains a detailed timeline of his Confederate Army service, including his resignation because he was "weary and worn." (Submitted on April 6, 2023, by Duane and Tracy Marsteller of Murfreesboro, Tennessee.) 
 
Dr. Thomas Isom's Drug Store and Medical Office Marker image. Click for full size.
Photographed by Duane and Tracy Marsteller, April 1, 2023
2. Dr. Thomas Isom's Drug Store and Medical Office Marker
 
 
Credits. This page was last revised on April 6, 2023. It was originally submitted on April 6, 2023, by Duane and Tracy Marsteller of Murfreesboro, Tennessee. This page has been viewed 278 times since then and 27 times this year. Photos:   1, 2. submitted on April 6, 2023, by Duane and Tracy Marsteller of Murfreesboro, Tennessee.
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Jun. 28, 2026