Gonzales in Gonzales County, Texas — The American South (West South Central)
Holmes Hospital
A native of Gonzales County, Dr. George Holmes (1881-1948) began practicing medicine in Gonzales in 1915. His dream of a fully equipped hospital for the county seat was realized with the completion of this hospital building in 1921. Constructed by contractor Fred Miesenhelder, the two-story red brick building features a Spanish tile roof and a bracketed porch. It served as hospital and administrative offices until 1978.
Erected 1984 by Texas Historical Commission. (Marker Number 2513.)
Topics. This historical marker is listed in these topic lists: Architecture • Science & Medicine. A significant historical year for this entry is 1921.
Location. 29° 30.191′ N, 97° 26.6′ W. Marker is in Gonzales, Texas, in Gonzales County. It is at the intersection of Saint Louis Street (State Highway 146) and Darst Street, on the right on Saint Louis Street. Touch for map. Marker is at or near this postal address: 1118 St Louis St, Gonzales TX 78629, United States of America. Touch for directions.
Regionally, this marker is in Hill Country. It is also in the American South. Globally, it is in North America, a Gulf of Mexico state, the Western Hemisphere, the Western World, and the Anglosphere. Historically, it finds itself in what was once New Spain, the Republic of Texas, one of the Confederate States of America, and the Antebellum South.
Other nearby markers. At least 8 other markers are within walking distance of this marker: The Immortal 32 (about 300 feet away, measured in a direct line); Gonzales Memorial Museum and Amphitheatre (about 300 feet away); Gonzales Memorial Museum (about 400 feet away); Route of Gen. Sam Houston (about 400 feet away); Sarah Ponton Eggleston (about 500 feet away); The Eggleston House (about 600 feet away); Charles T. Rather House (approx. 0.2 miles away); Cemetery Square (approx. 0.3 miles away). Touch for a list and map of all markers in Gonzales.
Credits. This page was last revised on February 10, 2026. It was originally submitted on February 9, 2026, by Dave W of Co, Colorado. This page has been viewed 76 times since then. Photos: 1, 2, 3. submitted on February 9, 2026, by Dave W of Co, Colorado. • James Hulse was the editor who published this page.


