Fitzrovia in City of Westminster in Greater London, England, United Kingdom — Northwestern Europe (the British Isles)

Discovery of Aldosterone

Photographed by Andrew Ruppenstein, April 26, 2026

1. Discovery of Aldosterone Marker

Inscription.
It was at the Middlesex Hospital Medical School on this site that the hormone aldosterone, essential for life, was first discovered in 1952 by James F Tait, Sylvia A Simpson, Hilary M Grundy

Erected 2020 by Westminster City Council, The Society for Endocrinology.

Topics and series. This historical marker is listed in this topic list: Science & Medicine. In addition, it is included in the City of Westminster Green Plaques series list. A significant historical year for this entry is 1952.

Location. 51° 31.203′ N, 0° 8.298′ W. Marker is in City of Westminster, England, in Greater London. It is in Fitzrovia. It is at the intersection of Cleveland Street and Foley Street, on the left when traveling north on Cleveland Street. Touch for map. Marker is at or near this postal address: 33 Cleveland Street, City of Westminster, England W1T 4JG, United Kingdom. Touch for directions.

Regionally, this marker is in the Greater South East.

Globally, it is on the Atlantic Ocean,

in the North Atlantic Region,

in Europe,

in Atlantic Europe,

on one of the British Isles,

in the Western World,

and in the Anglosphere.

Paid Advertisement

Click or scan to see
this page online

Historically, it finds itself in what was once the Roman Empire.

Other nearby markers. At least 8 other markers are within walking distance of this marker: Sister Dorothy Louise Thomas GC (within shouting distance of this marker); Fitzroy Place (within shouting distance of this marker); Olaudah Equiano (within shouting distance of this marker); Charles Dickens (within shouting distance of this marker); a different marker also named Olaudah Equiano (about 90 meters away, measured in a direct line); Sir Robert Smirke (about 120 meters away); Henry Fuseli (about 150 meters away); Joseph Lister (about 210 meters away). Touch for a list and map of all markers in City of Westminster.

Also see . . .
1. Sylvia Agnes Sophia Tait (Wikipedia). Overview:

Sylvia Agnes Sophia Tait (née Wardropper, 8 January 1917 – 28 February 2003, known as Sylvia Simpson from 1941 to 1956) was an English biochemist. She worked with her second husband, James Francis Tait, from 1948 until her death in 2003, a partnership described by the Oxford Dictionary of National Biography as "one of the most successful examples of husband-wife scientific collaboration".
Photographed by Andrew Ruppenstein, April 26, 2026

2. Discovery of Aldosterone Marker - wide view
Together, they discovered and identified the hormone aldosterone, the last of a series of naturally occurring biologically potent steroid hormones to be isolated and identified between the 1920s to the 1950s, after the androgens, oestrogens, and glucocorticoid hormones. Aldosterone is part of the mechanism that regulates blood pressure, and causes conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. It is thought to be responsible for 15 per cent of cases of high blood pressure.

(Submitted on April 26, 2026.)

2. James Francis Tait (Wikipedia). (Submitted on April 26, 2026.)

Additional keywords. plaque

Credits. This page was last revised on April 26, 2026. It was originally submitted on April 26, 2026, by Andrew Ruppenstein of Lamorinda, California. This page has been viewed 13 times since then. Photos: 1, 2. submitted on April 26, 2026, by Andrew Ruppenstein of Lamorinda, California.