Lake City in Florence County, South Carolina — The American South (South Atlantic)
115 & 117 E. Main St.
[Weaver's Drug Store]
| | Lake City Downtown Historic District | |

Photographed by Devry Becker Jones (CC0), May 21, 2026
1. 115 & 117 E. Main St. Marker
National Register of Historic Places Registration Form:
Click for more information.
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of Historic Places
South Carolina
Department of Archives
and History
115 & 117 E. Main St.
Lake City Downtown
Historic District
Erected by South Carolina Department of Archives and History.
Topics. This historical marker is listed in these topic lists: Architecture • Industry & Commerce • Science & Medicine.
Location. 33° 52.337′ N, 79° 45.239′ W. Marker is in Lake City, South Carolina, in Florence County. It is on East Main Street (Business U.S. 378) east of South Acline Street (South Carolina Road 21-264), on the right when traveling east. Touch for map. Marker is at or near this postal address: 117 East Main Street, Lake City SC 29560, United States of America. Touch for directions.
Regionally, this marker is in South Carolina’s Pee Dee. It is also in the American South and specifically in the Deep South. Globally, it is in North America, the Western Hemisphere, the Western World, and the Anglosphere. Historically, it finds itself in what was once the territory of the Mississippian Culture, one of the original Thirteen Colonies, one of the Confederate States of America, and the Antebellum South.
Other nearby markers. At least 8 other markers are within walking distance of this marker: 111 East Main Street (a few steps from this marker); 118 East Main Street (a few steps from this marker); 116 East Main Street (a few steps from this marker); 124 East Main Street (within shouting distance of this marker); 130 East Main Street (within shouting distance of this marker); 133 East Main Street (within shouting distance of this marker); 104 & 106 East Main Street (within shouting distance of this marker); H.H. Singletary Building (within shouting distance of this marker). Touch for a list and map of all markers in Lake City.
Regarding 115 & 117 E. Main St.. 115 and 117 East Main Street [Weaver's Drug Store], ca. 1914-1920
A one-story brick building with two glass and metal storefronts separated by a central brick pier and containing flat metal awnings on each. A soldier course and shallow corbeled cornice visually separate the storefronts from the upper facade. Brick panels with cast stone corner blocks adorn each of the two upper
Credits. This page was last revised on July 9, 2026. It was originally submitted on May 25, 2026, by Devry Becker Jones of Washington, District of Columbia. This page has been viewed 11 times since then. Photos: 1, 2. submitted on May 25, 2026, by Devry Becker Jones of Washington, District of Columbia.
