Lake City in Florence County, South Carolina — The American South (South Atlantic)
104 & 106 East Main Street
[Floyd's Drug Company/Roper's Drug Company; Strickland's Jewelers]
| | Lake City Downtown Historic District | |
Photographed by Devry Becker Jones (CC0), May 21, 2026
1. 104 & 106 East Main Street Marker
National Register of Historic Places Registration Form
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of Historic Places
South Carolina
Department of Archives
and History
104 & 106 East Main Street
Lake City Downtown
Historic District
Topics. This historical marker is listed in these topic lists: Architecture • Industry & Commerce • Science & Medicine. A significant historical year for this entry is 1920.
Location. 33° 52.362′ N, 79° 45.254′ W. Marker is in Lake City, South Carolina, in Florence County. It is on East Main Street (U.S. 378) east of North Acline Avenue (South Carolina Road 21-264), on the left when traveling east. Touch for map. Marker is at or near this postal address: 104 East Main Street, Lake City SC 29560, United States of America. Touch for directions.
Regionally, this marker is in South Carolina’s Pee Dee. It is also in the American South and specifically in the Deep South. Globally, it is in North America, the Western Hemisphere, the Western World, and the Anglosphere. Historically, it finds itself in what was once the territory of the Mississippian Culture, one of the original Thirteen Colonies, one of the Confederate States of America, and
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Other nearby markers. At least 8 other markers are within walking distance of this marker: H.H. Singletary Building (a few steps from this marker); Huey Cooper 1873 - 1978 (a few steps from this marker); 116 East Main Street (within shouting distance of this marker); 111 East Main Street (within shouting distance of this marker); 118 East Main Street (within shouting distance of this marker); 115 & 117 E. Main St. (within shouting distance of this marker); Palmetto State Bank Robbery (within shouting distance of this marker); 124 East Main Street (within shouting distance of this marker). Touch for a list and map of all markers in Lake City.
Regarding 104 & 106 East Main Street. 104 and 106 East Main Street [Floyd's Drug Company/Roper's Drug Company; Strickland's Jewelers], ca. 1920
A one-story brick building with asymmetrical glass and metal storefronts and large cloth awnings covering the storefront cornices. There are horizontal brick panels above each storefront. The building cornice is corbeled brick and there is a brick capped parapet on the building. The larger store [104 East Main] once housed Floyd's
Credits. This page was last revised on July 9, 2026. It was originally submitted on May 25, 2026, by Devry Becker Jones of Washington, District of Columbia. This page has been viewed 9 times since then. Photos: 1, 2. submitted on May 25, 2026, by Devry Becker Jones of Washington, District of Columbia.
