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Rochester in Olmsted County, Minnesota — The American Midwest (Upper Plains)
 

Dr. William Worrall Mayo

Historic Site

 
 
Dr. William Worrall Mayo Marker image. Click for full size.
Photographed by Cosmos Mariner, September 8, 2023
1. Dr. William Worrall Mayo Marker
Inscription.
On this site in 1865 Dr. William Worrall Mayo constructed his first (and only) dedicated medical office building in Rochester. Later destroyed by fire, it was described as “a neat and pleasant office” (Rochester City Post, June 10, 1865).

This historical marker was placed in 2019 through the efforts of John Kruesel, his friends and family.
 
Erected 2019 by John Kruesel, his friends and family.
 
Topics. This historical marker is listed in this topic list: Science & Medicine. A significant historical year for this entry is 1865.
 
Location. 44° 1.22′ N, 92° 27.85′ W. Marker is in Rochester, Minnesota, in Olmsted County. It is on 3rd Street Southwest just east of 1st Avenue Southwest, on the left when traveling west. Touch for map. Marker is at or near this postal address: 22 3rd Street Southwest, Rochester MN 55902, United States of America. Touch for directions.

Regionally, this marker is in Southeast Minnesota. It is also in the American Midwest and in the Corn Belt. Globally, it is in North America, the Western Hemisphere, the Western World, and the Anglosphere. Historically, it finds itself in what was once
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Rupert’s Land and also the territory of the Mississippian Culture.

Other nearby markers. At least 8 other markers are within walking distance of this marker: Conley Maass Downs Building (about 400 feet away, measured in a direct line); The Plummer Building (about 700 feet away); Rochester Public Library Building (approx. 0.2 miles away); The Chateau Theatre (approx. 0.2 miles away); Calvary Episcopal Church (approx. 0.2 miles away); The Rochester Armory Building (approx. 0.3 miles away); Birth of the Minnesota Education Association (approx. 0.3 miles away); Central Park Plaza (approx. 0.4 miles away). Touch for a list and map of all markers in Rochester.
 
Also see . . .
1. Site of Dr. W.W. Mayo’s first medical office unveiled in Rochester (KAAL TV).
Excerpt:  The site marks the location of where Dr. William Worrall Mayo built his first and only dedicated medical office in Rochester. A business card listing the W.W. Mayo office located on Third Street led to a scavenger hunt through newspapers to pin down the exact site. “The discovery was that WW Mayo had his first office in a wooden building here. I believe that it’s
Dr. William Worrall Mayo Marker image. Click for full size.
Photographed by Cosmos Mariner, September 8, 2023
2. Dr. William Worrall Mayo Marker
The marker is mounted at eye level on the north facade of the building at this location today.
between 1865 and 1867 then it burned down it was a wooden building a majority of the buildings on this block burned down at that time,” Owner of John Kruesel’s General Merchandise & Auction Company John Kruesel said.
(Submitted on July 28, 2026, by Cosmos Mariner of Cape Canaveral, Florida.) 

2. William Worrall Mayo (Wikipedia).
Excerpt:  William Worrall Mayo (May 31, 1819 – March 6, 1911) was an English American medical doctor and chemist. He is best known for establishing the private medical practice that later evolved into the Mayo Clinic. On April 24, 1863, Mayo was named examining surgeon for the first Minnesota draft board headquartered in Rochester, Minnesota. He left his family for that position and soon found the new city to his liking, so they joined him there in early 1864. Mayo opened a solo medical practice in Rochester in 1863. He partnered with W. A. Hyde from February to June 1864 before going back to solo practice. In November 1867, Mayo entered into a partnership with pharmacist O. W. Anderson, which lasted until November 1869 when Mayo left heading for Pennsylvania and New York City to study surgical techniques.
Dr. Mayo image. Click for full size.
Photographed by Cosmos Mariner, September 8, 2023
3. Dr. Mayo
This enlarged vintage photo of Dr. Mayo with his horse and buggy is in the window on the right side of the historical marker.
In 1874, Mayo returned to Rochester to rebuild his practice and re-entered local politics.
(Submitted on July 28, 2026, by Cosmos Mariner of Cape Canaveral, Florida.) 
 
The building at this location today (<i>northeast elevation</i>) image. Click for full size.
Photographed by Cosmos Mariner, September 8, 2023
4. The building at this location today (northeast elevation)
 
 
Credits. This page was last revised on July 28, 2026. It was originally submitted on July 27, 2026, by Cosmos Mariner of Cape Canaveral, Florida. This page has been viewed 8 times since then. Photos:   1, 2. submitted on July 27, 2026, by Cosmos Mariner of Cape Canaveral, Florida.   3, 4. submitted on July 28, 2026, by Cosmos Mariner of Cape Canaveral, Florida.
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Aug. 2, 2026