Madison in Dane County, Wisconsin — The American Midwest (Great Lakes)
Understanding Immunity
College of Agricultural and Life Sciences
Photographed By William J. Toman, June 25, 2010
1. Understanding Immunity Marker
Inscription.
Understanding Immunity. College of Agricultural and Life Sciences. In the mid-1940s University of Wisconsin geneticist Ray Owen noticed a surprising fact about non-identical cattle twins. Each twin had two kinds of blood cells, its own and those of its twin. In ordinary transfusions, such mixing of blood cells often leads to sever immunological reaction. Owen realized that when bloods are exchanged early in development, each twin somehow learns to tolerate the other's cells. This discovery of "immune tolerance" helped to explain how an organism can tell its own cells from foreign ones, and fueled a revolution in immunology. The nature of immune tolerance is central to studies of organ transplantation, cancer, and autoimmune disease.
In the mid-1940s University of Wisconsin geneticist Ray Owen noticed a surprising fact about non-identical cattle twins. Each twin had two kinds of blood cells, its own and those of its twin. In ordinary transfusions, such mixing of blood cells often leads to sever immunological reaction. Owen realized that when bloods are exchanged early in development, each twin somehow learns to tolerate the other's cells. This discovery of "immune tolerance" helped to explain how an organism can tell its own cells from foreign ones, and fueled a revolution in immunology. The nature of immune tolerance is central to studies of organ transplantation, cancer, and autoimmune disease.
Location. 43° 4.567′ N, 89° 24.948′ W. Marker is in Madison, Wisconsin, in Dane County. Marker is at the intersection of Linden Drive and Observatory Drive, on the right when traveling north on Linden Drive. The marker is on the west side of the Animal Science Building on the University of Wisconsin campus.
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Touch for map. Marker is at or near this postal address: 1675 Observatory Drive, Madison WI 53706, United States of America. Touch for directions.
The marker is on the right, in front of the Animal Science Building.
Photographed By William J. Toman, June 25, 2010
3. Agricultural Hall
According to the UW web site, "Built in 1902, Agricultural Hall was designed as the administrative and research home of the College of Agricultural and Life Sciences. The building remains almost entirely unmodified and was added to the National Register of Historic Places in 1985."
Photographed By William J. Toman, June 24, 2010
4. Auditorium and Library, Hall of Agriculture
Back entrance to Agricultural Hall
Photographed By William J. Toman, June 24, 2010
5. Detail on Agricultural Hall
Symbol of the College of Agricultural and Life Sciences
Credits. This page was last revised on December 30, 2019. It was originally submitted on July 8, 2010, by William J. Toman of Green Lake, Wisconsin. This page has been viewed 586 times since then and 12 times this year. Photos:1, 2, 3, 4, 5. submitted on July 8, 2010, by William J. Toman of Green Lake, Wisconsin. • Bill Pfingsten was the editor who published this page.