Amarillo in Potter County, Texas — The American South (West South Central)

Route 66 in Amarillo

Photographed by Mansfieldphoto.com, May 9, 2026

1. Route 66 in Amarillo Marker

Inscription. Commonly called the "Main Street of America" and also the "Mother Road," Route 66 became the first paved transcontinental highway in the U.S. spanning from Chicago to Los Angeles, the route in Texas crossed 7 panhandle counties over 177 miles. Route 66 was popular with automobile tourists. The road was important in the development of Sixth Street and the San Jacinto area in Amarillo, which was the only large urban city on the Texas route. In 1994 the area was listed in the National Register of Historic Places, and has become the focus of local preservation efforts.

Erected 1996 by Texas Historical Commission. (Marker Number 4365.)

Topics and series. This historical marker is listed in this topic list: Roads & Vehicles. In addition, it is included in the U.S. Route 66 series list. A significant historical year for this entry is 1926.

Location. 35° 12.691′ N, 101° 51.973′ W. Marker is in Amarillo, Texas, in Potter County. It is on SW Sixth Avenue, on the right when traveling west. Marker is between Georgia and McMasters Street. Touch for map. Marker is in this post office area: Amarillo TX 79106, United States of America. Touch for directions.

Regionally, this marker is on the Texas Panhandle.

It is also on the American Great Plains,

specifically on the Southern Plains,

and specifically on the High Plains.

Globally, it is in North America,

a Gulf of Mexico state,

the Western Hemisphere,

the Western World,

and the Anglosphere.

Historically, it finds itself in what was once New Spain,

the Comanchería,

the Dust Bowl,

the Republic of Texas,

and one of the Confederate States of America.

Other nearby markers. At least 8 other markers are within 2 miles of this marker, measured as the crow flies: Amarillo Natatorium ("The Nat") (within shouting distance of this marker); Bussey Building

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(about 300 feet away, measured in a direct line); Northwest Texas Hospital School of Nursing (approx. ¼ mile away); Dutch Mill Service Station & Café (approx. half a mile away); Texas Ivy Antiques, Amarillo, Texas (approx. 0.6 miles away); Juan de Padilla (approx. 1.1 miles away); Wild Horse Lake (approx. 1.2 miles away); St. Mary's Academy (approx. 1.2 miles away). Touch for a list and map of all markers in Amarillo.

Photographed by Bill Kirchner, November 19, 2015

2. Route 66 in Amarillo Marker

Photographed by Bill Kirchner, November 19, 2015

3. Route 66 in Amarillo Marker

Photographed by Bill Kirchner, November 19, 2015

4. Route 66 in Amarillo Marker

Credits. This page was last revised on May 31, 2026. It was originally submitted on December 19, 2015, by Bill Kirchner of Tucson, Arizona. This page has been viewed 991 times since then and 43 times this year. Photos: 1. submitted on May 31, 2026, by James Hulse of Medina, Texas. 2, 3, 4. submitted on December 19, 2015, by Bill Kirchner of Tucson, Arizona.