Madison in Dane County, Wisconsin — The American Midwest (Great Lakes)

Controlling Blood Clotting

College of Agricultural and Life Sciences

Photographed By William J. Toman, July 1, 2012

1. Controlling Blood Clotting Marker

Inscription. Through the misfortune of a Wisconsin farmer, biochemist Karl Paul Link and his University of Wisconsin associates were handed the keys to discovery of anticlotting factors. Farmer Ed Carlson in February 1933 brought to Link sweet clover hay that he thought might be involved in the death of his cattle from uncontrollable bleeding. Link and students isolated and identified dicumarol as the anticlotting agent in the spoiled hay. Link, and biochemists Mark Stahmann and M. Ikawa, then synthesized comparable compounds including Warfarin, which is widely used to treat thrombosis and other clotting disorders. It also proved to be a highly effective rodenticide.

This marker is made possible by a grant from the UW Foundation

Erected 2001 by the UW Foundation.

Topics and series. This historical marker is listed in these topic lists: Agriculture • Animals • Education • Science & Medicine. In addition, it is included in the University of Wisconsin series list. A significant historical month for this entry is February 1933.

Location. 43° 4.42′ N, 89° 24.674′ W. Marker is in Madison, Wisconsin, in Dane County. Marker is at the intersection of University Avenue and Babcock Drive, on the right when traveling west on University Avenue. The marker

Paid Advertisement

Click on the ad for more information.
Please report objectionable advertising to the Editor.

Click or scan to see
this page online

is at the southwest corner of the Biochemistry Building on the campus of the University of Wisconsin-Madison. Touch for map. Marker is at or near this postal address: 420 Henry Mall, Madison WI 53706, United States of America. Touch for directions.

Other nearby markers. At least 8 other markers are within walking distance of this marker. Eliminating Pellagra (a few steps from this marker); First Chemical Synthesis of a Gene (within shouting distance of this marker); Discovery of Vitamins A and B (within shouting distance of this marker); Treatment of Iron Deficiency Anemia (within shouting distance of this marker); Pioneering Bacterial Genetics (about 300 feet away, measured in a direct line); Pioneering Human Genetics (about 300 feet away); Vitamin D Production Ends Rickets (about 400 feet away); Genetically Superior Crops (about 600 feet away). Touch for a list and map of all markers in Madison.

More about this marker. This marker is part of a series commemorating the sesquicentennial of the University of Wisconsin-Madison.

Photographed By William J. Toman, July 1, 2012

2. Controlling Blood Clotting Marker

This is the corner of the Biochemistry Building at the intersection of University Avenue and Babcock Drive, with the marker just to the left of the corner.

Credits. This page was last revised on March 28, 2018. It was originally submitted on July 2, 2012, by William J. Toman of Green Lake, Wisconsin. This page has been viewed 543 times since then and 11 times this year. Last updated on March 27, 2018, by J. I. Waldby of Livingston, Montana. Photos: 1, 2. submitted on July 2, 2012, by William J. Toman of Green Lake, Wisconsin. • Andrew Ruppenstein was the editor who published this page.