Elizabethtown in Hardin County, Illinois — The American Midwest (Great Lakes)

Anna Bixby Trail/Historic Rose Hotel

Photographed by Jason Voigt, June 9, 2026

1. Anna Bixby Trail/Historic Rose Hotel Marker

Inscription.
Anna Bixby Trail
This point marks the beginning of an early trail traveled by Anne Hobbs Bixby, mid-wife and herb doctor, while caring for the sick in the Rock Creek community, 8 miles northeast of here. A century before recognition was given by the American Medical Society, Anna made the discovery that white snakeroot was the cause of an epidemic of milk-sickness which ravaged the area round 1830.

Historic Rose Hotel
Has overlooked the beautiful Ohio River at Elizabethtown since 1812.

Topics. This historical marker is listed in these topic lists: Industry & Commerce • Science & Medicine • Women. A significant historical year for this entry is 1830.

Location. 37° 26.714′ N, 88° 18.271′ W. Marker is in Elizabethtown, Illinois, in Hardin County. It is at the intersection of Main Street and Locust Street, on the left when traveling south on Main Street. Touch for map. Marker is at or near this postal address: 195 Main St, Elizabethtown IL 62931, United States of America. Touch for directions.

Regionally, this marker is in Southern Illinois — Little Egypt

and in Shawnee Hills.

It is also in the American Midwest,

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in the Ohio River Valley,

and in the Corn Belt.

Globally, it is in North America,

the Western Hemisphere,

the Western World,

and the Anglosphere.

Historically, it finds itself in what was once the territory of the Mississippian Culture

and also the Northwest Territory.

Other nearby markers. At least 8 other markers are within 3 miles of this marker, measured as the crow flies: Welcome to the Historic Rose Hotel Bed and Breakfast (within shouting distance of this marker); War Memorial (about 700 feet away, measured in a direct line); You Are Not Forgotten (about 700 feet away); The Elizabethtown First Baptist Church (approx. 0.2 miles away); Fluorite Mining (approx. 2.8 miles away); Mine It, Mill It, Ship It (approx. 2.9 miles away); The Ohio River Scenic Byway (approx. 2.9 miles away); Rosiclare: The Fluorite Center of Hardin County, the United States and the World (approx. 2.9 miles away). Touch for a list and map of all markers in Elizabethtown.

Also see . . . Anna Pierce Hobbs Bixby on Wikipedia. Bixby was either born in Tennessee, or Philadelphia, Pennsylvania. Many believe she may have been the first female

Photographed by Jason Voigt, June 9, 2026

2. Anna Bixby Trail/Historic Rose Hotel Marker

On the side of Historic Rose Hotel

doctor in the state of Illinois. (Submitted on June 19, 2026, by Jason Voigt of Glen Carbon, Illinois.)

National Register of Historic Places plaque image. Click for full size.

Photographed by Jason Voigt, June 9, 2026

3. National Register of Historic Places plaque

Credits. This page was last revised on June 19, 2026. It was originally submitted on June 19, 2026, by Jason Voigt of Glen Carbon, Illinois. This page has been viewed 9 times since then. Photos: 1, 2, 3. submitted on June 19, 2026, by Jason Voigt of Glen Carbon, Illinois.