Tiburon in Marin County, California — The American West (Pacific Coastal)
Ayala Cove
Preventing the Spread of Disease
Close your eyes and imagine this cove full of ships and sailors, buildings and noisy machines, doctors, cleaning staff, and nervous travelers hoping to complete their voyages.
When the US Quarantine Station opened here in 1891, ships and people coming from other countries risked spreading yellow fever, cholera, plague, and other diseases.
Congress decided a quarantine station would help. Travelers could be held there for weeks to be sure they were not sick. Their clothes and baggage were disinfected and sterilized. The ships and cargo were fumigated to kill rats, fleas, and other disease-carrying pests.
In time, medical advances and better screening reduced the need for the quarantine station, and it was shut down.
Did You Know?
For centuries, Ayala Cove served as a landing point for Coast Miwok people. Later, Spanish sailors anchored here.
Superheated steam, sulphur, formaldehyde, sodium cyanide, ammonia, and hydrochloric acid were used to disinfect cargo and luggage.
Quarantined travelers could wait up to six weeks before being allowed to continue to their destinations.
Juan Manuel de Ayala, the first European to anchor at Angel Island, named it Isla de los Angeles. He landed on August 2, 1775, an important Catholic feast day celebrating Our Lady of the Angels, Saint Mary.
Right Panel:
Discover
Timelss Harbor
With its natural harbor and sheltered waters, Ayala Cove has served as the main landing point on Angel Island for generations.
While You Are Here
1. Exhibits and a short film make the visitor center an excellent starting point for discovering Angel Island and its rich history.
2. Look for moon-shaped hills of dirt in the grassy areas, marking the home of the Angel Island mole.
3. If you dont have much time, walk up Perimeter Road above Point Ione. It offers a nice view of Sausalito and Tiburon, as well as sailboats on clear days.
4. Notice the contrast between the eucalyptus trees, which the army planted in rows like corn, and the much less orderly native trees across the road.
5. Protected waters make the Ayala Cove beach a great spot to splash in the water.
Safety Starts Here
Stay on trails and out of closed buildings to avoid injuries. By following these simple steps, you also help protect the parks resources.
Left Panel:
Angel Island State Park
(map)
Erected by California Department of Parks & Recreation.
Topics. This historical marker is listed in these topic lists: Parks & Recreational Areas • Science & Medicine • Waterways & Vessels. A significant historical year for this entry is 1891.
Location. 37° 51.942′ N, 122° 26.099′ W. Marker is in Tiburon, California, in Marin County. It can be reached from Angel Island. Angel Island is located north of Alcatraz Island and is the largest island in the San Francisco Bay. It is accessed by ferry, private boat, watercraft, or kayak. Touch for map. Marker is in this post office area: Belvedere Tiburon CA 94920, United States of America. Touch for directions.
Regionally, this marker is in California’s San Francisco Bay Area, in the North Coast, and specifically on the Coast Ranges. It is also on the American Pacific Coast. Globally, it is in North America, on the Ring of Fire, in the Pacific Rim, in the Western Hemisphere, in the Western World, and in the Anglosphere. Historically, it finds itself in what was once New Spain and also Mexicos Alta California.
Other nearby markers. At least 8 other markers are within walking distance of this marker: Isolating Disease (within shouting distance of this marker); Angel Island (within shouting distance of this marker); Medical Officers at Home (about 300 feet away, measured in a direct line); a different marker also named Angel Island (about 400 feet away); Protecting the Public Health (approx. 0.2 miles away); a different marker also named Ayala Cove (approx. 0.2 miles away); Melting Glaciers + Rising Seas = (approx. Ό mile away); Camp Reynolds (approx. 0.4 miles away). Touch for a list and map of all markers in Tiburon.
Another marker is no longer nearby. A Golden Port (was approx. 0.4 miles away but has been permanently removed).
More about this marker. The three resin panels are mounted between four metal poles on the trail southeast of the former bachelor officers quarters, now a visitor center & museum.
Regarding Ayala Cove. The entire island is a state park, except for Point Blunt on the southeastern tip, which is controlled by the U.S. Coast Guard.
Also see . . . Angel Island State Park.
"Angel Island State Park, the largest natural island in the San Francisco Bay, offers some of the best views of the surrounding Bay Area. With great hiking trails and many other recreational opportunities readily available, Angel Island is truly a hidden gem in the midst of the urban Bay Area."(Submitted on August 6, 2022, by Joseph Alvarado of Livermore, California.)
Credits. This page was last revised on January 4, 2026. It was originally submitted on August 6, 2022, by Joseph Alvarado of Livermore, California. This page has been viewed 364 times since then and 22 times this year. Photos: 1, 2, 3, 4, 5. submitted on August 6, 2022, by Joseph Alvarado of Livermore, California. 6. submitted on August 19, 2022, by Joseph Alvarado of Livermore, California. 7. submitted on August 6, 2022, by Joseph Alvarado of Livermore, California. 8, 9, 10. submitted on August 18, 2022, by Joseph Alvarado of Livermore, California. • Syd Whittle was the editor who published this page.









